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KMID : 1145120170150010023
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Asian Journal of Beauty and Cosmetology
2017 Volume.15 No. 1 p.23 ~ p.31
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Effects of Corchorus olitorius L. (Molokhia) Extracts as Functional Cosmetic Materials
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Kim Mi-Jung
Park Se-Yeon
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Abstract
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Purpose: This study investigated the possibility of using Corchorus olitorius L. (C. olitorius L., Molokhia) extracts as functional cosmetic materials.
Methods: The total extracts of C. olitorius L. were fractionated into an oil layer and an aqueous layer and called extract A and B, respectively. Staphylococcus aureus (S. aureus)and Pseudomonas aeruginosa (P. aeruginosa) were used to investigate the anti-microbial effects of extract A and B at concentrations of 0.1 and 0.2 mg/mL. The 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium, inner salt (MTS) assay was conducted to determine the cytotoxicity of C. olitorius L. extract A and B (10, 20, and 40 μg/mL). Anti-oxidant effects were examined using a fluorescent dye, and the effects on collagen synthesis were analyzed by western blotting.
Results: Extract A and B showed anti-microbial effects against S. aureus and P. aeruginosa and were not toxic to the Hs68 or HaCaT cell lines. The anti-oxidant effects of extract A and B were comparable with that of glutathione, a human anti-oxidant positive control. The C. olitorius L. extracts slightly restored collagen synthesis that decreased after ultraviolet (UV) stimulation.
Conclusion: These results suggest that C. olitorius L. extracts could become components of functional cosmetics.
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KEYWORD
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Corchorus olitorius L., Cytotoxicity, Anti-microbial effects, Anti-oxidant effects, Collagen synthesis
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